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Disease TYPHOID FEVER
   
Quotation “If Noah had been truly wise He would have scatted those two flies”
   
Definition An infectious febrile illness caused by ingetion of Salmonella Typhil, presenting with severe systemic manifestations.
   
Prognosis Good in the vast majority treated with the appropriate antibiotic.
   
Treatment

Suspect when fever is high, continuous lasting for over a week. Patient looks ill, with mind splenomegaly, no tachycardia, Leukopenia, and Widal test is positive.

Treatment.

Bed rest.

Small frequent feeds. Soft diet-Avoid chillies, spicy and oily foods. Maintain oral hygiene.

IV CIPLOX&actContent=TYPHOID FEVER&redTo=disease&drg_tid=35814'>CIPLOX&actContent=TYPHOID FEVER&redTo=disease&drg_tid=35793'>CIPLOX&actContent=TYPHOID FEVER&redTo=disease&drg_tid=35814'>CIPLOX 200mg bd x 2-4 days, Then Tab. CIPLOX&actContent=TYPHOID FEVER&redTo=disease&drg_tid=35814'>CIPLOX&actContent=TYPHOID FEVER&redTo=disease&drg_tid=35793'>CIPLOX&actContent=TYPHOID FEVER&redTo=disease&drg_tid=35814'>CIPLOX 500mg bd for 10-15 days. Or

IV Oflox 200mg 12hourly x 2-4 days the Tab. Oflox 500 mg bd for 10-15 days. Or

IV CHLOROMYCETIN 1gm 6hourls x 2-4 days. Then Cap. CHLOROMYCETIN 500 mg 6 hourly for 2 weeks.

Tab. ULTRAGIN 6 hourly or S.O.S when there is fever.

Tab. RANTAC 150mg bd (acid inhibitors)

Tab. WYSOLONE 10mg 10mg x tds x 5 days, if the patient is toxic.

Tab. PERINORM 1 tds if there is comiting.

IV fluids during acute phase, as and when necessary.

If there is no response after 4-5 days;

Probably there is resistance to quinoloness and chloromycetcin

Inj. Cephaxone 1 gm IV BD to 6 hourly till fever is controlled, then orally tab. CETIL 500mg 1-2 BD for total 14 days. or

Tab. CEFI 400 mg 1BD for 10-14 days.

Tab. AZEE 1gm OD for 5 days.

Inj. Decadron 2cc IC 12 hourly for 2-3 days

In pregnant females, prefer third generation cephalosporin.

Prevention:

Vaccinate all contacts in home. Also vaccinate people who eat hotel food and outside water frequently.

Oral Typhoral – one capsule on alternate days, on empty stomach in morning, 3 doses. With booster every 5 hours.

Inj. Typhin Vi 0.5 ml IM, Booster every 3 years.


IV CHLOROMYCETIN

Tab. AZEE

Inj. Decadron

Tab. Typhoral

 

 

 

PERINORM RANTAC ULTRAGIN TYPHON WYSOLONE AZEE CEFI CEFAXONE INJ CETIL CHLOROMYCETIN CIPLOX CIPLOX OFLOX TABLETS OFLOX INFUSION 
   
General Measures Fluid and Electrolyte management especially correction of hypolalemia in paralytic ileus. Continuous nasogastric suction in paralytics ileusBland liquid, semisolid diet and bed rest until few days elapse after subsidence of fever.
   
Advice to Patient Avoidance of fecal oral transmission by proper hand washing after defecation
   
Follow Up If a Relapse is suspected.
   
Inadequate Response AS detailed under Drug Therapy
   
Prevention Type 21a Oral Vaccinne-Perhaps the best available for prevention today. 1 Capsule alternate day for 3 doses. Vi Capsular Polysacharide Typhoid Vaccine Not considered to be of much benefit. T.A.B. Vaccine WHO has recommended discontinuation as antibodies produced are different to those produced by disease.
   
Reference From Website: www.sums.ac.ir/~semj/vol1/jan2001/kazamifari.htm
   

 

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